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High-Throughput Experimentation Technology
Zyleris has developed a best-in-class high-throughput topical and transdermal formulation screening technology that is at least 20x faster than present industrial standard Franz Cell technology and lowering costs up to 90% per formulation. This technology utilizes Franz Cell principle in a high-throughput fashion. This technology offers the best of both worlds - speed associated with high-throughput experimentation and yet result compatibility with standard Franz Cell technology.
Main Technical Features
=> Modular, compact 108-cell high-throughput screening (HTS) experimentation station (size of the station: 12x11”)
=> Variable diffusion area from 0.2 to 1.0 cm2 (corresponding tissue membrane size: 5 mm to 11.5 mm. The 8.0 mm is the standard configuration)
=> All glass and Teflon construction to ensure chemical inertness
=> Applicable to all common galenic forms
=> Fast and easy sample collection mechanism particularly suitable for high-throughput operation
=> Controlled mixing/stirring
Advantages As Compared With Franz Cell Technology
=> Faster -> Higher Productivity. Throughputs at least 20x faster.
=> Cheaper -> Lower Cost Per Formulation. Lowering costs up to 90% per formulation.
=> And Better -> Less Skin Membrane Usage Yet Yields Higher Detection Sensitivity. Up to 5-20x higher detection sensitivity for a given active ingredient than Franz Cell technology with similar size of skin membrane. Smaller cells and less membrane use with high detection sensitivity. Particularly beneficial for active ingredient with low permeability or therapeutic dosage.
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