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High-Throughput Topical and Transdermal Formulation Screening - The High-Throughput Franz Cell Technology
Zyleris has developed a first-in-class, high-throughput topical and transdermal formulation screening technology that is up to 20x faster than present industrial standard Franz Cell technology and lowering costs up to 90% per formulation. This technology utilizes Franz Cell principle in a high-throughput fashion. It offers the best of both worlds - speed associated with high-throughput experimentation and yet data compatibility with standard Franz Cell technology.
Our high-throughput technology is fully validated against standard Franz Cell. In addition to our internal validation data available for your review, we are more than happy to run test formulations for you free-of-charge. The free service allows you to conduct your independent technology comparison and validation (transdermal mode only). Please contact us for details.
Main Technical Features
=> Modular, compact 108-cell high-throughput screening (HTS) experimentation station (size of the station: 12x11”)
=> Variable diffusion area from 0.2 to 1.0 cm2 (corresponding tissue membrane size: 5 mm to 11 mm. The 8 mm is the standard configuration)
=> All glass and Teflon construction to ensure chemical inertness
=> Applicable to all common galenic forms including gels, lotions, creams, ointments, serums, solutions, and patches
=> Fast, easy, and uniform sample collection mechanism particularly suitable for high-throughput operation and data reproducibility
=> Precision temperature control
=> Efficient mixing (eliminates potential stagnant layer and air bubbles without creating vortex effect)
Advantages as Compared with Franz Cell Technology
=> Faster -> Higher Productivity
=> Cheaper -> Lower Cost Per Formulation
=> And Better -> Parallel Operation - Minimize Variation Among HTS Cells
What Our Technology Can Do for You
=> Evaluate topical and transdermal formulations faster, cheaper and better
=> Discover penetration enhancers and retardants to achieve optimal release profile.
=> Screen compound library to identify drug candidates for topical and transdermal delivery
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